産品名稱

産品編号

CAS NO.     

規格         

價格（元） 

(-)-Epigallocatechin Gallate (EGCG) (-)-表沒食子兒茶素沒食子酸酯 

MZ3651-20MG      

989-51-5

20mg

238

(-)-Epigallocatechin Gallate (EGCG) (-)-表沒食子兒茶素沒食子酸酯

MZ3651-100MG

989-51-5

100mg

598

(-)-Epigallocatechin Gallate (EGCG) (-)-表沒食子兒茶素沒食子酸酯

MZ3651-500MG

989-51-5

500mg

2188

文獻1，Rasheed NO et al.Nephro-toxic effects of intraperitoneally injected EGCG in diabetic mice: involvement of oxidative stress, inflammation and apoptosis. Sci Rep. 2017 Jan 18;7:40617. PMID: 28098182

體内研究：

動物(wù)模型（Animal Model）：Male Swiss albino mice weighing 25–30 g

藥物(wù)配制（Preparation）：Teavigo, a highly purified extract containing 94% EGCG, dissolved in saline

注射劑量（Dosages）：Mice were randomly divided into 4 groups 8 mice each except group 4 in which 15 mice were used: Group 1 received saline served as normal control. Group 2 received a single dose of STZ (150 mg/kg, i.p) used as diabetic control.Group 3 received EGCG (100 mg/kg, i.p) dissolved in saline for 4 days. Group 4 received STZ as in group 2 then the diabetic animals were injected after 48 hrs with EGCG as in group 3. After 48 hrs of STZ injection, animals with blood glucose level ≥200 mg/dl were selected as diabetic animals.

給藥途徑（Administration）：Intraperitoneal (i.p.) injection

文獻2，Pan C et al.NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage. Oxid Med Cell Longev. 2017;2017:3172692. PMID: 28698767

體内研究：

動物(wù)模型（Animal Model）：Eight-week-old male mice that was successfully induced as diabetic mice.

藥物(wù)配制（Preparation）：EGCG dissolved in normal saline

注射劑量（Dosages）：The diabetic mice and age-matched controls were treated daily by subcutaneously injected EGCG (100 mg/kg≥98%, dissolved in normal saline) or normal saline daily, for a total period of 24 weeks. Blood glucose was recorded on days 0, 28, 56, 84, 112, 140, and 168, after diabetes onset.

給藥途徑（Administration）：Subcutaneous (s.c.) injection